Soft (bio)molecule desorption and transfer for enhanced mass spectrometric analysis and solvent-free multilayer buildup

Arnaud Delcorte, Vincent Delmez, Thomas Daphnis, Benjamin Tomasetti, Samuel Bertolini, Christine Dupont-Gillain

Institute of Condensed Matter and Nanoscience, Université catholique de Louvain, Belgium.

Benchmarking 3D-OrbiSIMS for Structural Modelling of Native Biomolecular Complexes

Aditi N Borkar, Ceri Staley, Anna Kotowska, Christopher Waugh, Shannon Ward, Julie Watts

University of Nottingham, United Kingdom

Soft landing simulations of lysozymes desorbed by argon cluster bombardment

Samuel Bertolini, Arnaud Delcorte

Universite Catholique de Louvain, Belgium

Evaluating the Effect of Water Overlayer on Sputtering of Trehalose by Water Cluster Projectiles – Computer Simulations Study

Michał Jakub Kański, Zbigniew Postawa

Jagiellonian University, Faculty of Physics, Astronomy and Applied Computer Science, Smoluchowski Institute of Physics, Łojasiewicza 11, 30-348 Kraków, Poland

The evolution and future of SIMS in the microelectronic industry

Alexis Franquet¹, Valentina Spampinato^1,2

1: IMEC, Belgium; 2: Università degli Studi di Catania, Italy

OrbiSIMS Investigations of Engine Deposits from Real-World Systems and the Laboratory

Joseph Lamb^1,2, Max Edney^1,2, Matteo Spanu², Jim Barker¹, Colin Snape², David Scurr², Emily Smith², Craig Stoppiello^2,3, Jacqueline Reid¹, Edward Wilmot¹, Morgan Alexander²

1: Innospec; 2: University of Nottingham; 3: University of Queensland

Correlative characterization of conversion coatings by using time-of-flight secondary ion mass spectrometry and salt spray tests

Damien Cossement¹, Emeline Lachery¹, Arno Schut², Patrick Karpe², Sylvain Desprez¹, Mireille Poelman¹

1: Materia Nova, 3 Avenue Nicolas Copernic, 7000 Mons, Belgium; 2: Axcentive, 593 Chemin de Champouse 13320 Bouc-Bel-Air, France

Microelectronic applications of in-situ FIB sectioning in the TOF-SIMS

Jean-Paul Barnes¹, Gregory L. Fisher²

1: Univ. Grenoble Alpes, CEA, Leti, F-38000, Grenoble, France; 2: Physical Electronics, Chanhassen, Minnesota 55317, United States

Correlative TOF-SIMS/SEM imaging of photosynthetic organisms

Claire Seydoux, Pierre-Henri Jouneau, Jean-Paul Barnes

CEA Grenoble, France

Combined ToF-SIMS and C-AFM characterization on WS₂ 2D transition metal dichalcogenide layers

Valentina Spampinato^1,3, Yuanyuan Shi^2,3, Jill Serron³, Albert Minj³, Benjamin Groven³, Thomas Hantschel³, Paul van der Heide³, Alexis Franquet³

1: Università degli Studi di Catania, Italy; 2: School of Microelectronics, University of Science and Technology of China, Hefei, China; 3: IMEC, Kapeldreef 75, 3001 Leuven, Belgium

Trends and prospects of Focused Ion Beam platforms coupled with SIMS systems

Jean-Nicolas Audinot, Patrick Philipp, Olivier De Castro, Antje Biesemeier, Hung Quang Hoang, Tom Wirtz

Luxembourg Institute of Science and Technology, Luxembourg

Production of synthetic homogenous U-Pu samples for determination of rL-SNMS suppression rates

Paul Hanemann, Stefan Bister, Manuel Raiwa, Sandra Reinhard, Darcy van Eerten, Aaron Lehnert, Clemens Walther

Institute of Radioecology and Radiation Protection, Leibniz Universität Hannover, Germany

Smaller proteins, bigger data

Anna Kotowska

University of Nottingham, United Kingdom

Subcellular spatial distribution of protein turnover in neuronal progenitor cells

Alicia A. Lork¹, Stefania Rabasco¹, Carl Ernst², Silvio O. Rizzoli³, Nhu T.N. Phan¹

1: Department of Chemistry and Molecular Biology, University of Gothenburg, Sweden; 2: Human Genetics, McGill University, H4H1R3 Montreal, Canada; 3: Department of Neuro- and Sensory Physiology, University Medical Center Göttingen; Center for Biostructural Imaging of Neurodegeneration, Göttingen, Germany

Impact of polymer film structure on interactions with peptides, proteins and bacteria strains

Kamil Awsiuk¹, Yurij Stetsyshyn², Andrzej Budkowski¹, Joanna Raczkowska¹, Natalia Janiszewska¹

1: M. Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University; 2: Lviv Polytechnic National University

Targeted molecular imaging with correlative NanoSIMS: Applications to study protein organization and turnover in neuronal cells

Stefania Rabasco¹, Selda Kabatas², Paola Agüi-Gonzalez^2,3, Alicia Andrea Lork¹, Emmanuel Berlin¹, Felipe Opazo³, Silvio O. Rizzoli^2,3, Nhu T.N. Phan¹

1: Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden; 2: Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, Göttingen, Germany; 3: Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, Göttingen, Germany

Atomic depth resolution for atomically thin materials

Paweł Piotr Michałowski

Łukasiewicz Research Network - Institute of Microelectronics and Photonics, Poland

Insights on OLED degradation mechanisms by correlative TOF-SIMS and XPS

Claire Guyot, Jean-Paul Barnes, Olivier Renault, Tony Maindron

Univ. Grenoble Alpes, CEA, Leti, F-38000, Grenoble, France

ToF-SIMS Surface Analysis of Stains on Bond Pads and Passivation layer – key enabler to identify the contamination source to prevent reoccurrence

Patrick Rostam-Khani, Jos Philipsen, Shreya Nandi

NXP Semiconductors, The Netherlands

Exploring additively manufactured heterostructures of functional materials: focus on interfaces

Jonathan Austin¹, Feiran Wang¹, Negar Gilani¹, Yundong Zhou², Gustavo F. Trindade², Ian Gilmore², Christopher J. Tuck¹, Richard J.M. Hague¹, Ricky D. Wildman¹, Lyudmila Turyanska¹, Geoffrey Rivers¹

1: Centre for Additive Manufacturing, Faculty of Engineering, University of Nottingham, Nottingham, NG8 1BB, UK; 2: National Centre of Excellence in Mass Spectrometry Imaging, National Physical Laboratory, Teddington, TW11 0LW, UK

An Anthology of Integrative ToF-SIMS Imaging

Sebastiaan Van Nuffel^1,2

1: M4i, Maastricht University, The Netherlands; 2: Faculty of Science and Engineering, Maastricht University, The Netherlands

Using OrbiSIMS as an Alzheimer’s disease screening tool to investigate ApoE4-mediated molecular alteration of H4 neuroglioma cells

Li {Jennifer} Lu¹, Anna M. Kotowska¹, Stefanie Kern¹, Min Fang², Timothy R Rudd², Morgan R. Alexander¹, David J. Scurr¹, Zheying Zhu¹

1: School of Pharmacy, The University of Nottingham, University Park Campus, NG7 2RD, UK; 2: National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, EN6 3QG UK

ToF-SIMS as a matured asset in the plant physiology toolbox? Tracking down salt tolerance mechanisms in rose leaves.

Arne Krause¹, Stefanie Janine Jung², Volker Wissemann², Anja Henss¹

1: Institute of Physical Chemistry and Centre for Material Research, Justus-Liebig-Universität Gießen, Germany; 2: Institute of Systematic Botany, Justus Liebig University Giessen, Germany

ORBITRAP-SIMS IMAGING REVEALS CELL-TYPE SPECIFIC LOCALIZATION OF TOMATO SECONDARY METABOLITES AND ALLOWS PUTATIVE METABOLITE ANNOTATION

Uwe Heinig¹, Julia Zakel², Alexander Pirkl², Yonghui Dong¹, Matthias Kleine-Boymann², Asaph Aharoni¹

1: Weizmann Institute of Science, Rehovot, Israel; 2: IONTOF GmbH, Münster, Germany

The Utility of Surface-Induced Dissociation in Molecular Identification

Gregory Lawrence Fisher¹, Shin-ichi Iida²

1: Physical Electronics, United States of America; 2: ULVAC-PHI, Japan

Development of Novel High Energy Cluster Ion Beam Methodology for Molecular Analysis and Imaging

Matija Lagator, Sadia Sheraz, Nicholas P. Lockyer

The University of Manchester, United Kingdom

Automated Unattended TOF-SIMS Analysis of Insulator Samples using PHI nanoTOF3

Shin-ichi Iida¹, Gregory Fisher²

1: ULVAC-PHI, Japan; 2: Physical Electronics, USA

Evaluating the depth distribution of organics within porous oxide nanostructures - FIB'n'SIMS vs. cross section mapping vs. depth profiles of hybrid nanoarchitectures

Patrick Hartwich, Gabriel Onyenso, Christian Pritzel, Swathi Naidu Vakamulla Raghu, Manuela S. Killian

Chemistry and Structure of novel Materials, University of Siegen, Germany

High-resolution FIB-STIM-SIMS imaging of bio samples under cryogenic conditions

Antje Kristina Biesemeier, Tatjana Taubitz, Olivier De Castro, Tom Wirtz

Advanced Instrumentation for Nano-Analytics, Materials Research and Technology Department, Luxembourg Institute of Science and Technology, Belvaux, Luxembourg

In-situ interface investigations with FIB-SIMS platform

Pablo Maria Delfino^1,2, Guillaume Lamblin³, Tom Wirtz¹, Jean-Nicolas Audinot¹

1: Advanced Instrumentation for Nano-Analytics (AINA), MRT Department, Luxembourg Institute of Science and Technology (LIST), Belvaux, Luxembourg; 2: University of Luxembourg, 4365 Esch-sur-Alzette, Luxembourg; 3: Transparent and Optically Tuneable, MRT Department, Luxembourg Institute of Science and Technology (LIST), Belvaux, Luxembourg

Multiomic Imaging Using a High Resolution ToF-SIMS Instrument

Kimberly G. Garcia, Ron M.A. Heeren, Sebastiaan Van Nuffel

Maastricht MultiModal Molecular Imaging Institute (M4i), Maastricht University, The Netherlands

Identification of Markers for Papillomavirus Induced Tumors Using ToF-SIMS Imaging

Mariya A. Shamraeva¹, Theodore Visvikis¹, Stefanos Zoidis¹, Jiafen Hu^2,3, Yusheng Zhu³, Neil D. Christensen^2,3, Ian G. M. Anthony¹, Sebastiaan Van Nuffel¹

1: Maastricht MultiModal Molecular Imaging Institute (M4i), Maastricht University Universiteitssingel 50, 6229 ER Maastricht, The Netherlands; 2: The Jake Gittlen Laboratories for Cancer Research, Hershey, PA 17033, USA; 3: Pathology department, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA

ToF-SIMS imaging of fingermarks on cylindrical bullet casings

Long Jiang, Matthew Piggott, David J. Scurr, James S. Sharp

University of Nottingham, United Kingdom

Characterization of proton-lithium exchange in nickel-rich layered oxides using ToF-SIMS

Steffen Schröder, Kilian Vettori, Anja Henss

Institute of Physical Chemistry & Center of Materials Research, Justus Liebig University Giessen, Heinrich-Buff-Ring 17, 35392 Giessen, Germany

Vitamin C skin permeation explored ex-vivo and in-vivo using Secondary Ion Mass Spectrometry

Anna Helena Trzaska, David Scurr, Mark O'mahony

University of Nottingham, United Kingdom

Detection of Multiply Charged Peptides using ToF-SIMS

Sadia Sheraz¹, Felicia Green², Zoltan Takats^2,3, Josephine Bunch⁴, Nick Lockyer⁵

1: Department of Materials and Henry Royce Institute, University of Manchester, UK; 2: The Rosalind Franklin Institute, Harwell Campus, UK; 3: Department of Surgery and Cancer, Imperial College London, London, UK; 4: National Physical Laboratory, Teddington, UK; 5: Department of Chemistry, University of Manchester, Manchester, UK

Study of phase formation in ceramic perovskite oxides by combining TOF-SIMS, EDS/SEM and XRD analysis

Laura Cecilia Baqué

INN-CNEA-CONICET, Argentine Republic

In situ SIMS Analysis of Pulsed Laser Deposited Li-containing Thin Films

Xiaochun Huang^1,2, Natacha Ohannessian^1,2, Christof W. Schneider¹, Thomas Lippert^1,2

1: Division for Research with Neutrons and Muons (NUM), Paul Scherrer Institut, Switzerland.; 2: Department of Chemistry and Applied Biosciences, ETH Zurich, Switzerland.

Study of mouse brain tissue with ToF-SIMS and Hybrid SIMS

Hyun Kyong Shon¹, Jin Gyeong Son¹, Sun Young Lee¹, Jeong Hee Moon², Ga Seul Lee², Kyoung-Shim Kim², Tae Geol Lee¹

1: KRISS, Korea, Republic of (South Korea); 2: KRIBB, Korea, Republic of (South Korea)

Classification and Feature Extraction of ToF-SIMS Microplastic spectra with Machine Learning

Jin Gyeong Son, Hyun Kyong Shon, In-Ho Lee, Tae Geol Lee

Korea Researh Institute of Standards and Science, Korea, Republic of (South Korea)

Secondary electron and chemical imaging of a PS-PMMA blend utilizing a multimodal instrument combining Helium Ion Microscope and SIMS

Victor Benito Olmos^1,2, Alexander Shaplov³, Tom Wirtz¹, Jean-Nicolas Audinot¹

1: Advanced Instrumentation for Nano-Analytics (AINA), MRT Department, Luxembourg Institute of Science and Technology (LIST), Belvaux, Luxembourg; 2: University of Luxembourg, 4365 Esch-sur-Alzette, Luxembourg; 3: Materials Research and Technology (MRT) Department, Luxembourg Institute of Science and Technology (LIST), 5 avenue des Hauts Fourneaux, L4362, Esch-sur-Alzette, Luxembourg

A correlative approach for the investigation of metal accumulation in the human brain using different high resolution and high sensitivity SIMS imaging techniques

Zahraa Hasan Berro^1,5, Maria Angels Subirana², Clementine Warres³, Dirk Schaumloeffel², Tatjana Taubitz¹, Jean-Nicolas Audinot¹, Tom Wirtz¹, Fabio Zucca⁴, Luigi Zecca⁴, Antje Biesemeier¹

1: Advanced Instrumentation for Nano-Analytics, Materials Research and Technology Department, Luxembourg Institute of Science and Technology, Belvaux, Luxembourg; 2: CNRS, Université de Pau et des Pays de l'Adour, E2S UPPA, Institut des Sciences Analytiques et de Physico-Chimie pour l'Environnement et les Matériaux (IPREM), UMR 5254, 64000 Pau, France; 3: NMI Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstraße 55, 72770 Reutlingen, Germany; 4: Institute of Biomedical Technologies, National Research Council of Italy, Segrate, Milan, Italy; 5: University of Luxembourg, 4365 Esch-sur-Alzette, Luxembourg

Chronic Sleep Deprivation Exacerbates the Testicular Oxidative Stress and Impairs the Sperm Motility by Disrupting Zinc Expression in the Gonads

Fu-Der Mai¹, Li-You Chen², Ting-Yi Renn¹, Rou-An Yao³, Hung-Ming Chang¹

1: Taipei Medical University, Taiwan; 2: Chung Shan Medical University, Taiwan; 3: National Taiwan University, Taiwan

Understanding Biomolecule-Fabric Interactions for Improved Fabric Care

Joseph William Roberts¹, Andrew Leslie Hook¹, Matthew Piggott¹, Anna M. Kotowska¹, Ross Sellars²

1: University of Nottingham, Nottingham, United Kingdom; 2: Croda, Goole, United Kingdom

Development and characterisation of a drug dosed biomimetic reference material for a SIMS VAMAS inter-laboratory study to study sensitivity and linearity

Jean-Luc Vorng¹, Carla Newman², Andy West², Ian Gilmore¹

1: National Physical Laboratory, Teddington, Middlesex, TW11 0LW; 2: GlaxoSmithKline, Gunnel Wood Road, Stevenage, Hertfordshire, SG1 2NY, UK

Characterisation of Aluminium-lithium alloys using NanoSIMS and EPMA

Yizhuo Ding

University of Manchester, United Kingdom

Chemical structure and morphology of carbonized date seeds

Kion Norrman, Ibtisam Bin Sharfan, Mahmoud A. Abdulhamid

KFUPM, Saudi Arabia

ToF-SIMS and XPS examination of human cornea and its gelatin methacryloyl hydrogel-based model for devising a cornea-on-a-chip

Jaroslaw Mazuryk¹, Alexis Franco¹, Shadi Bazazordeh^1,2, Thomas Reichert², Jan Vanfleteren², Bo Van Durme³, Sandra Van Vlierberghe³, Joris Van Meenen⁴, Bert Van Der Bogerd⁴, Carina Koppen⁴, Claude Poleunis¹, Christine Dupont-Gillain¹, Arnaud Delcorte¹

1: Bio & Soft Matter, Institute of Condensed Matter and Nanosciences, Université catholique de Louvain, Belgium; 2: Centre for Microsystems Technology (CMST), Imec and Ghent University, Belgium; 3: ) Polymer Chemistry and Biomaterials Group, Centre of Macromolecular Chemistry, Ghent University, Belgium; 4: Ophthalmology, Visual Optics and Visual Rehabilitation, Department of Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Belgium

Enhancing Photocatalytic Hydrogen Evolution on Anatase TiO₂ Nanosheets via Vanadium Co-catalyst Decoration

Setareh Orangpour, Shiva Mohajernia, Seyedsina Hejazi, Manuela S. Killian

Siegen universität, Germany

Cryogenic FIB-SIMS imaging for mapping elemental ions within bacterial cells

Hannah Ochner

MRC Laboratory of Molecular Biology, United Kingdom

Chemical analysis of functional 0D materials used in inkjet printing of optoelectronics devices

Gustavo F. Trindade¹, Jisun Im², Jonathan Austin², Geoffrey Rivers², Yundong Zhou¹, Yinfeng He², Feiran Wang², Richard Hague², Ian S. Gilmore¹, Lyudmila Turyanska²

1: National Physical Laboratory, United Kingdom; 2: Centre for Additive Manufacturing, Faculty of Engineering, University of Nottingham, Nottingham, UK