Conference Agenda

Virginia Chiocchia, Konstantina Chalkou, Orestis Efthimiou, Tasnim Hamza, Georgia Salanti

Virginia Chiocchia, Konstantina Chalkou, Orestis Efthimiou, Tasnim Hamza, Georgia Salanti

Virginia Chiocchia, Konstantina Chalkou, Orestis Efthimiou, Tasnim Hamza, Georgia Salanti

Virginia Chiocchia, Konstantina Chalkou, Orestis Efthimiou, Tasnim Hamza, Georgia Salanti

Confidence intervals in two-stage adaptive enrichment designs

Enyu Li, Nigel Stallard, Ekkehard Glimm, Dominic Magirr, Peter Kimani

Dynamic Bayesian Sample Size Re-Estimation: Balancing Historical and Real-Time Data in Adaptive Clinical Trials

Niamh Anne Fitzgerald, James Wason, Adrian Mander

MAMS with patient reported outcomes and treatments with different modalities: how should we handle a differential placebo effect?

Isobel Grace Landray, Jennifer Nicholas, James Carpenter

Multi-arm multi-stage (MAMS) randomised selection designs: With an application to miscarriage and surgical platform trials

Babak Choodari-Oskooei, Alexandra Blenkinsop, Lee Middleton, Kelly Handley, Versha Cheed, Lee Priest, Emily Fox, Leah Fitzsimmons, Rima Smith, Adam Devall, Thomas Pinkney, Arri Coomarasamy, Mahesh KB Parmar

A test for treatment differences using allocation probabilities in response-adaptive clinical trials

Stina Zetterstrom, David S. Robertson, Sofía S. Villar

Compatible Effect Estimation and Hypothesis Testing in Drug Regulation

Samuel Pawel, Leonhard Held

Opportunities to speed up IVD adoption and patient access in the UK: the pre-eclampsia testing timeline

Katie Scandrett, Joy Allen, Jon Deeks, Julia Eades, Ashton Harper, Christopher Hyde, Yemisi Takwoingi, David Wells

Statistical review of regulatory requirements for AI diagnosis

NAOKI ISHIZUKA, TARO SHIBATA

Validating Physiologically-based Pharmacokinetic Models using the Continuous Ranked Probability Score: Beyond Being Correct on Average

Laurens Sluijterman, Marjolein van Borselen, Rick Greupink, Joanna intHout

Conditional Marketing Authorisation based on the Intermediate Endpoint of a Randomised Clinical Trial: Dual or Co-Primary Endpoints?

Nele Henrike Thomas, Xiaofei Liu, Elina Asikanius, Anika Großhennig, Armin Koch

Using a foundation model for detecting and reducing site-specific differences in federated meta-analysis of regression models

Patric Tippmann, Max Behrens, Harald Binder

Sample size calculations for prediction model development: A general Bayesian-framework using posterior distributions to examine expected performance, degradation and stability

Richard D Riley, Rebecca Whittle, Mohsen Sadatsafavi, Glen Martin, Alexander Pate, Gary Collins, Joie Ensor

Efficient Utilization of Dose-Schedule Grids for Optimal Therapeutic Outcomes in Non-Oncology Settings

Lars Andersen, Mitchell Thomann, Thomas Jaki

On the interplay between prior weight and vague variance in Robust Mixture Priors

Marco Ratta, Gaëlle Saint-Hilary, Pavel Mozgunov

Bayesian nonparametric methods for inferring causal effects of longitudinal treatments amidst missing covariate data

Liangyuan Hu

Assumption-lean modeling for patient-centered decision-making

Stijn Vansteelandt, Georgi Baklicharov

Causal inference targeting a concentration index for studies of health inequalities

Mohammad Ghasempour, Xavier de Luna, Per Gustafsson

Rethinking the Win Ratio: A Causal Framework for Hierarchical Outcome Analysis

Julie Josse, Mathieu Even

Assessing individual-level uncertainty of causal predictions through the causal effective sample size

Doranne Thomassen, Daniala Weir, Marleen Kunneman, Nan van Geloven

Estimating Win Ratio for Prioritized Composite Outcomes in the Presence of Noncompliance

Md. Muhitul Alam, Mahbub A.H.M. Latif, M. Iftakhar Alam, Abdus S Wahed

A general approach to fitting multistate cure models based on an extended-long-format data structure

Yilin Jiang, Harm van Tinteren, Marta Fiocco

Calibration of cause-specific absolute risk for external validation using each cause-specific hazards model in the presence of competing events

Sarwar Islam Mozumder, Sarah Booth, Richard Riley, Mark Rutherford, Paul Lambert

Multi-state models with restricted transition windows: The impact of time scale choice

Georgy Gomon, Ilaria Prosepe, Rachel Knevel, Saskia le Cessie

Integrating Landmarking and Competing Risks in Survival Analysis with Machine Learning Techniques

Shirin Sultana, Dr. Md Hasinur Rahaman Khan

Survival without vs after transition to the intermediate event in a non-markovian “illness-death” model: application to heart transplant data

Davide Paolo Bernasconi, Lorenzo Del Castello, Laura Antolini

A framework for estimating, investigating and using the correlation between multiple time-to-event endpoints in a group sequential trial

Anne Lyngholm Soerensen, Paul Blanche, Henrik Ravn, Christian Pipper

Likelihood adaptively incorporated external aggregate information with uncertainty for survival data

Jing Ning

A new statistical test to compare probability of being in response (PBR) with application to a study in oncology

Norbert Hollaender, Ekkehard Glimm

One-sample survival tests for non-proportional hazards in oncology clinical trials

Chloé Szurewsky, Guosheng Yin, Gwénaël Le Teuff

Efficiency of Nonparametric Superiority Tests Based on Restricted Mean Survival Time Versus the Logrank Test Under Proportional Hazards

Dominic Magirr

Estimating the new event-free survival

Judith Vilsmeier, Maral Saadati, Kaya Miah, Axel Benner, Hartmut Döhner, Jan Beyersmann

Marginal Matched Pairs Cox Regression

Jana Kinzel, Jan Beyersmann

Using Restricted Mean Survival Time under proportional hazards in a non-inferiority randomised trial with time-to-event outcome

Matteo Quartagno, Matt Nankivell, Tim Morris, Ian White

Variable selection methodology for illness-death model with interval censored data

Ariane BERCU, Agathe GUILLOUX, Cécile PROUST-LIMA, Hélène JACQMIN-GADDA

Modelling the time-varying effect of hormonal treatment on metastasis-free survival among ER+ breast cancer patients - a natural history modelling approach

Letizia Orsini, Alessandro Gasparini, Kamila Czene, Keith Humphreys