Conference Agenda

Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).

 
 
Session Overview
Location: Biozentrum U1.111
Biozentrum, 302 seats
Date: Sunday, 24/Aug/2025
9:00am
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10:30am
Targeted Learning
Oliver Dukes, Stijn Vansteelandt, Shaun Seaman
Location: Biozentrum U1.111
 
11:00am
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12:30pm
Targeted Learning
Location: Biozentrum U1.111
 
1:30pm
-
3:00pm
Targeted Learning
Location: Biozentrum U1.111
 
3:30pm
-
5:00pm
Targeted Learning
Location: Biozentrum U1.111
 
Date: Monday, 25/Aug/2025
9:00am
-
9:30am
Formal opening
Location: Biozentrum U1.111
 

Formal opening

Kaspar Rufibach

9:30am
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10:45am
Confidence distributions: new tools to design, adapt and analyse clinical trials
Ian Marschner
Location: Biozentrum U1.111
Chair: Thomas Jaki
 
11:30am
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1:00pm
When worlds collide: Common methodological themes in meta-analysis, causal inference, and hybrid trial design
Location: Biozentrum U1.111
Chair: David Phillippo
 

Brief Introduction

David Phillippo



Combining information from multiple and diverse sources to answer causal questions

Issa J. Dahabreh



Doubly robust augmented entropy balancing for externally controlled clinical trials and indirect treatment comparisons

Antonio Remiro-Azocar



Meta-analytic Framework Using Individual Patient Data: A Case Study from Alopecia Arrieta

Satrajit Roychoudhury

2:00pm
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3:30pm
AI-driven multi-omics data integration
Location: Biozentrum U1.111
Chair: Niko Beerenwinkel
 

Generative AI for Unlocking the Complexity of Cells

Maria Brbic



Machine Learning for Multi-Omics Integration: Advancing Rare Disease Diagnostics in Pediatric Acute Care

Julia Vogt



Correspondence problems in multi-omic data

Kjong-Van Lehmann

4:00pm
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5:30pm
Prediction modelling meets causal inference for clinical decision making
Location: Biozentrum U1.111
Chair: Ruth Keogh
 

From prediction to treatment decision: aligning development, evaluation and monitoring

Wouter A.C. van Amsterdam



Dynamic Prediction of Survival Benefit to Inform Liver Transplant Decisions in Hepatocellular Carcinoma Patients

Pedro Miranda Afonso, Hau Liu, Michele Molinari, Dimitris Rizopoulos



Clinical applications of predictions under interventions

Nan van Geloven

Date: Tuesday, 26/Aug/2025
9:15am
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10:45am
Mathematical and Statistical Modelling in the Life Sciences: Seeking causal explanations
Location: Biozentrum U1.111
Chair: Jack Kuipers
 

In silico simulations of cancer-immune interactions to aid clinical trial design and execution

Johannes Textor, Jeroen Creemers



Evolutionary dynamics of cancer progression and response to treatment

Ivana Bozic



Using DAGs and dynamical simulations to explore and understand causal links

Theis Lange

11:30am
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1:00pm
Optimizing efficiency in adaptive trial designs
Location: Biozentrum U1.111
Chair: Katherine Lee
 

How can we foster a sensible use of adaptive designs for regulatory decision-making?

Frank Petavy



Optimizing Treatment Allocation in Platform Trials: A Need for New Rules?

Marta Bofill Roig, Martin Posch



Confirmatory adaptive enrichment designs with a continuous biomarker

Nigel Stallard

Date: Wednesday, 27/Aug/2025
9:00am
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10:30am
Cracking causal questions: Estimands for reliable and clinically relevant evidence
Location: Biozentrum U1.111
Chair: Marcel Wolbers
 

Chasing Shadows: How Implausible Assumptions Skew Our Understanding of Causal Estimands

Kelly Van Lancker, Stijn Vansteelandt



Paving the ground for breakthrough innovations in Alzheimer’s Disease drug development with the estimand framework and causal inference

Paul DELMAR, Marion Monchalin, Rachid Abbas



Estimating causal overall survival estimands in the presence of treatment switching using multi-state models

Alexandra Bühler, Tobias Mütze, Lisa Hampson, Jiali Wang, Tomas Haas

11:00am
-
11:15am
Session chair's introduction
Vanessa Didelez
Location: Biozentrum U1.111
 
11:15am
-
12:15pm
Statistical and causal perspectives on machine learning in estimating individualized treatment strategies
Erica E. M. Moodie
Location: Biozentrum U1.111
Chair: Vanessa Didelez
 
12:15pm
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1:30pm
ISCB Annual General Meeting
Location: Biozentrum U1.111
2:00pm
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3:30pm
Improving replicability in clinical biostatistics
Location: Biozentrum U1.111
Chair: Anne-Laure Boulesteix
 

Questionable Research Practices - From Small Errors to Research Misconduct

Leonhard Held



Improving the replicability of applied and methodological research

Sabine Hoffmann



Method benchmarking in computational biology - current state and future perspectives

Charlotte Soneson



Software sensitivity analysis in medical and methodological research

Tim P. Morris

4:00pm
-
5:30pm
Generative AI in clinical research and drug development (BBS invited session)
Location: Biozentrum U1.111
Chair: Giusi Moffa
 

(Generative) AI in medicine: Where does statistics come into play?

Sarah Friedrich



Do Single-Cell Transformers Understand Gene Regulation? A Cautionary Benchmark

Simon Anders, Constantin Ahlmann-Eltze, Wolfgang Huber



Panel Discussion

Giusi Moffa

Date: Thursday, 28/Aug/2025
9:15am
-
10:45am
Mini-Symposium 1: Causal Inference for Improved Clinical Collaborations: A Practicum
Location: Biozentrum U1.111
 

Introduction to Causal Inference

Giusi Moffa



Case Study Practicum

Breakout Groups

11:30am
-
1:00pm
Mini-Symposium 1: Causal Inference for Improved Clinical Collaborations: A Practicum
Location: Biozentrum U1.111
 

Case Study Overviews

- -



Panel Discussion

- -

2:00pm
-
3:30pm
Mini-Symposium 4: Enhancing Cancer Clinical Trials with Patient-Reported Outcomes: Insights from SISAQOL-IMI
Location: Biozentrum U1.111
 

Session 1: Introduction

Johannes Giesinger



Session 2: Randomised Clinical Trials

Jammbe Musoro



Session 3: Single Arm Trials

Saskia Le Cessie



Session 4: Results Communication and Visualization

Flora Mazerolle



Session 5: PRO Score Interpretation Thresholds

Johannes Giesinger



Panel discussion

- -

4:00pm
-
5:30pm
Mini-Symposium 4: Enhancing Cancer Clinical Trials with Patient-Reported Outcomes: Insights from SISAQOL-IMI
Location: Biozentrum U1.111
 

Session 1: Introduction

Johannes Giesinger



Session 2: Randomised Clinical Trials

Jammbe Musoro



Session 3: Single Arm Trials

Saskia Le Cessie



Session 4: Results Communication and Visualization

Flora Mazerolle



Session 5: PRO Score Interpretation Thresholds

Johannes Giesinger



Panel discussion

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