Conference Agenda
Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).
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Session Overview |
| Date: Monday, 25/Aug/2025 | ||||
| 9:00am - 9:30am |
Formal opening Location: Biozentrum U1.111 |
Formal opening Location: Biozentrum U1.131, U1.141, U1.101 & ETH E27, E23, E21 Livestream of the plenary |
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| 9:30am - 10:45am |
Confidence distributions: new tools to design, adapt and analyse clinical trials Ian Marschner University of Sydney, Sydney, Australia Location: Biozentrum U1.111 |
Confidence distributions: new tools to design, adapt and analyse clinical trials Location: Biozentrum U1.131, U1.141, U1.101 & ETH E27, E23, E21 Livestream of the plenary
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| 10:45am - 11:30am |
Coffee Break |
Poster Exhibition: M / Monday posters Location: Poster Location Longitudinal Psychological Status and Risk of Major Cardiovascular Events (MCE) in Individuals with Pre-Existing Myocardial Infarction: A Joint Modeling Approach Cardio-metabolic traits and its socioeconomic differentials among school children including MONW phenotypes in India: A baseline characteristics of LEAP-C cohort External validation of SMART2 model for recurrent cardiovascular risk Multi-disease risk models to target concomitant diseases and their interactions: Insights on cardio-renal-metabolic syndrome in England Machine learning methods for analyzing longitudinal health data streams: A comparative study Evaluating the fairness of a clinical prediction model for outcomes following psychological treatment in the UK’s National Health Service Multiple Imputation vs. Machine Learning for Handling Missing Data in Prediction Modelling: Which Best Balances Stability, Performance, and Computational Efficiency? Estimating rates of dental treatment and unmet dental need in a spatially explicit model in children in England, 2016-2018 Statistical Approach to Assess the Impact of Hospital Settings on Optimal Staffing Levels Real-time predictions of bed occupancy in hospitals. Positive and negative predictive values of diagnostic tests using area under the curve Freely accessible software for recruitment prediction and recruitment monitoring: Is it necessary? On moderation in a Bayesian log-contrast compositional model with a total. Interaction between extreme temperatures and pollutants on mortality Graphical inference in nonparametric hypothesis testing: A two-dimensional grid framework for analysis and visualization On regression analysis of interval-valued data based on order statistics Two-sided Beyesian simultaneous credible bands in linear regression model Cell composition analysis with unmeasured confounding Temporal transcriptomic analysis of microexon alternative splicing in mouse neurodevelopmental genes A Robust Method for Accurate Reconstruction of 3D Genome Conformation from Hi-C Data Balancing Accuracy, Clinical Utility, and Explainability: A Machine Learning Approach to Prostate Cancer Prediction Development of a thyroid cancer recurrence prediction calculator: A regression approach A comparison of methods for modelling multi-state cancer progression using screening data with censoring after intervention ADHD and 10–Year Disease Progression from Initiating Pharmacotherapy for Hypertension to Death: A Multistate Modelling Analysis Understanding PSA Dynamics: Integrating Longitudinal Trajectories, Testing Patterns, and Disease Progression. Joint Modeling for Principal Stratification: Analyzing Stroke Events in CADASIL Patients Across NOTCH3 Variants Challenges in modelling neuropsychiatric symptoms in early Alzheimer's Disease Network models to decipher the Human exposome : application to food exposome patterns in the general population Study brain connectivity changes in Dementia with Lewy Bodies with Functional Conditional Gaussian Graphical Models LongiSurvSHAP: Explaining Survival Models with Longitudinal Features Prognostic Models for Recurrent Event Data Unlocking diagnosis code for longitudinal modeling through representations from large language models Machine Learning Perspectives in Survival Prediction Model Selection: Frequentist vs. Bayesian Approach Non-parametric methods for comparing survival functions with censored data: Exhaustive simulation of all possible beyond-observed censoring scenarios and computational analysis Tree-based methods for length-biased survival data Evaluating different pragmatic approaches for selecting the truncation time of the restricted mean survival time in randomized controlled trials Identifying risk factors for hospital readmission in home-based care: a study from a monographic paediatric cancer centre A web-application for predicting Serious Adverse Event for guiding the enrollment procedure in Clinical Trials with Machine Learning Methods Assessing the Overall Burden of Adverse Events in Clinical Trials: Approaches and Challenges Matching-adjusted indirect comparison of endoscopic and craniofacial resection for the treatment of sinonasal cancer invading the skull base Information borrowing in phase II randomized dose-ranging clinical trials in oncology Information borrowing in Bayesian clinical trials: choice of tuning parameters for the robust mixture prior A Bayesian approach to decision making in early development clinical trials : An R solution. Designing Clinical Trials in R with rpact and crmPack Leveraging on historical controls in the design and analysis of phase II clinical trials Design of a research project to evaluate the statistical utility after transformation of a CDISC database into OMOP format Introducing CAMIS: an open-source, community endeavor for Comparing Analysis Method Implementations in Software Assessing covariates influence on cure probability in mixture cure models using martingale difference correlation Aligning Estimators to Treatment Effects in the presence of Intercurrent Events in the Analyses of Safety Outcomes CUtools: an R package for clinical utility analysis of predictive models Impact of Particulate Matter 2.5 Levels on Chronic Obstructive Pulmonary Disease: An Analysis of Nationwide Claims Data in Thailand Changes in health services use of a cohort of COPD patients from a pre-pandemic to a COVID-19 pandemic period The ISARIC Clinical Epidemiology Platform: Standardized Analytical Pipelines for Rapid Outbreak Response Topic modelling and time-series analysis to explore methodological trend evolution Post-stroke facial palsy: prevalence on admission, risk factors, and recovery with hyperacute treatments Evaluating Outlier Detection Methods in Real-World Growth Data: A Sensitivity Analysis of Imperfect Data in a Cluster Randomised Controlled Trial Latent class analysis on intersectional social identities and mental wellbeing among ethnic minority youth in Aotearoa New Zealand Using multiple imputation in real-word data studies to aid in the identification of predictors of response while addressing missing data An imputation method for heterogeneous studies in Network Meta-Analysis: A Fully Conditional Specification approach using distance metrics Impact of lack of measurement invariance on causal inference in randomized controlled-trials including patient-reported outcome measures: a simulation study Evaluation of the Psychometric Qualities of Idiographic Patient Reported Outcome Measures (I-PROMs) for Patients Monitoring: PSYCHLOPS example Bias in the estimation of a psychometric function when using the PSI-method under optimal conditions – a simulation study Psychometric properties confirmation of the Multiple Sclerosis Autonomy Scale (MSAS) questionnaire evaluating patient autonomy in multiple sclerosis (MS) Learning heterogeneous treatment effect from multiple randomized trials to inform healthcare decision-making: implications and estimation methods Multiple imputation of missing viral load measurements in HIV treatment trials: a comparison of strategies A novel approach for assessing inconsistency in network meta-analysis: Application to comparative effectiveness analysis of antihypertensive treatments Investigating (bio)statistical literacy among health researchers in a Belgian university context: A framework and study protocol Balneotherapy for Peripheral Vascular Diseases: A Systematic Review with a Focus on Peripheral Arterial Disease and Chronic Venous Insufficiency Binomial Sum Variance Inequality correction of 95% CIs of percentages in multicentre studies ensures approximately 95% coverage with minimal width Sample size calculation methods for clinical trials using co-primary count endpoints Analysis of Composite Endpoint in Cardiovascular Device Clinical Trials Bayesian predictive monitoring using two-dimensional index for single-arm trial with bivariate binary outcomes Optimising covariate allocation at design stage using Fisher Information Matrix for Non-Linear Mixed Effects Models in pharmacometrics Unbiased Estimation for Hierarchical Models in Clinical Trials Sample size re-estimation for McNemar's test in a prospective randomized clinical trial on childhood glaucoma Bayesian bivariate analysis of phase II basket trials enabling borrowing of information Usefulness of the blinded sample size re-estimation for dose-response trials with MCP-Mod Quantification of allocation bias in clinical trials under a response-adaptive randomization procedure for binary response variables Assessment of Assay Sensitivity in Non-Inferiority Trials Using Aggregate Data from a Historical Trial: A Population Adjustment Approach Exploring methods for borrowing evidence across baskets or subgroups in a clinical trial: a simulation study Comparing The ED50 Between Treatment Groups Using Sequential Allocation Trials. A pre-study look into post-study knowledge: communicating the use(fulness) of pre-posteriors in early development design discussions Estimation and testing methods for delayed-start design as an alternative to single-arm trials in small clinical trials Dealing with missing values in adaptive N-of-1 trials Adaptive clinical trial design with delayed treatment effects using elicited prior distributions |
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| 11:30am - 1:00pm |
When worlds collide: Common methodological themes in meta-analysis, causal inference, and hybrid trial design Location: Biozentrum U1.111 Combining information from multiple and diverse sources to answer causal questions Doubly robust augmented entropy balancing for externally controlled clinical trials and indirect treatment comparisons Meta-analytic Framework Using Individual Patient Data: A Case Study from Alopecia Arrieta |
Efficient analyses of clinical trials Location: Biozentrum U1.131 The Power of Three. A Framework to Guide Analysis of Covariance in Randomised Clinical Trials. Stirring the pot: combining influence functions and Wald type tests for more powerful closed testing procedures Analyzing multi-center randomized trials with covariate adjustment while accounting for clustering Increasing efficiency of composite endpoint trials: Novel Bayesian latent variable framework with application to late-stage trials Ordinal Outcome Analysis in Neurological Trials: Current Practices and the Proportional Odds Debate |
Poster Highlights Location: Biozentrum U1.141 |
Dynamic borrowing and basket trials Location: Biozentrum U1.101 Utility-based optimization of basket trials A frequentist approach to dynamic borrowing A Power Prior Based Basket Trial Design for Unequal Sample Sizes Borrowing information in basket trials with different clinical outcomes via a common intermediate outcome Robust external information borrowing in hybrid-control clinical trial designs |
| Causal inference - dealing with bias Location: ETH E27 Proximal indirect comparison Selection bias of cause-specific hazard ratios: the impact of competing events qbaconfound: A flexible Monte Carlo probabilistic bias analysis to unmeasured confounding Selection bias due to omitting interactions from inverse probability weighting External reproduction of a proxy-based causal model estimating average survival effects of sequential vs concurrent chemo-radiotherapy in stage III NSCLC |
Survival analysis 1 Location: ETH E23 Standardized Survival Probabilities and Contrasts Between Hierarchical Units in Multilevel Survival Models Multimodal mixture regression on censored data with a cure fraction. Modelling & Assessing the Effect of Frailty and Longitudinal Measures in Time-to-Event Outcome: An application to Colorectal Cancers Adjusted Kaplan-Meier curves for partly unobserved group membership in paediatric stem cell transplantation studies Extended multi-stage drop-the-losers design for multi-arm clinical trials using binary and survival endpoints |
Prediction / prognostic modelling 1 Location: ETH E21 Developing a clinical prediction model with a continuous outcome: sample size calculations to target precise predictions Sequential sample size calculations for developing clinical prediction models: learning curves suggest larger datasets are needed for individual-level stability Determining the Sample Size for Risk Prediction Models with Clustered Binary Data Conformal prediction intervals for the individual treatment effect Effective sample size for Cox survival models: A measure of individual uncertainty in predictions |
Poster Exhibition: M / Monday posters Location: Poster Location Longitudinal Psychological Status and Risk of Major Cardiovascular Events (MCE) in Individuals with Pre-Existing Myocardial Infarction: A Joint Modeling Approach Cardio-metabolic traits and its socioeconomic differentials among school children including MONW phenotypes in India: A baseline characteristics of LEAP-C cohort External validation of SMART2 model for recurrent cardiovascular risk Multi-disease risk models to target concomitant diseases and their interactions: Insights on cardio-renal-metabolic syndrome in England Machine learning methods for analyzing longitudinal health data streams: A comparative study Evaluating the fairness of a clinical prediction model for outcomes following psychological treatment in the UK’s National Health Service Multiple Imputation vs. Machine Learning for Handling Missing Data in Prediction Modelling: Which Best Balances Stability, Performance, and Computational Efficiency? Estimating rates of dental treatment and unmet dental need in a spatially explicit model in children in England, 2016-2018 Statistical Approach to Assess the Impact of Hospital Settings on Optimal Staffing Levels Real-time predictions of bed occupancy in hospitals. Positive and negative predictive values of diagnostic tests using area under the curve Freely accessible software for recruitment prediction and recruitment monitoring: Is it necessary? On moderation in a Bayesian log-contrast compositional model with a total. Interaction between extreme temperatures and pollutants on mortality Graphical inference in nonparametric hypothesis testing: A two-dimensional grid framework for analysis and visualization On regression analysis of interval-valued data based on order statistics Two-sided Beyesian simultaneous credible bands in linear regression model Cell composition analysis with unmeasured confounding Temporal transcriptomic analysis of microexon alternative splicing in mouse neurodevelopmental genes A Robust Method for Accurate Reconstruction of 3D Genome Conformation from Hi-C Data Balancing Accuracy, Clinical Utility, and Explainability: A Machine Learning Approach to Prostate Cancer Prediction Development of a thyroid cancer recurrence prediction calculator: A regression approach A comparison of methods for modelling multi-state cancer progression using screening data with censoring after intervention ADHD and 10–Year Disease Progression from Initiating Pharmacotherapy for Hypertension to Death: A Multistate Modelling Analysis Understanding PSA Dynamics: Integrating Longitudinal Trajectories, Testing Patterns, and Disease Progression. Joint Modeling for Principal Stratification: Analyzing Stroke Events in CADASIL Patients Across NOTCH3 Variants Challenges in modelling neuropsychiatric symptoms in early Alzheimer's Disease Network models to decipher the Human exposome : application to food exposome patterns in the general population Study brain connectivity changes in Dementia with Lewy Bodies with Functional Conditional Gaussian Graphical Models LongiSurvSHAP: Explaining Survival Models with Longitudinal Features Prognostic Models for Recurrent Event Data Unlocking diagnosis code for longitudinal modeling through representations from large language models Machine Learning Perspectives in Survival Prediction Model Selection: Frequentist vs. Bayesian Approach Non-parametric methods for comparing survival functions with censored data: Exhaustive simulation of all possible beyond-observed censoring scenarios and computational analysis Tree-based methods for length-biased survival data Evaluating different pragmatic approaches for selecting the truncation time of the restricted mean survival time in randomized controlled trials Identifying risk factors for hospital readmission in home-based care: a study from a monographic paediatric cancer centre A web-application for predicting Serious Adverse Event for guiding the enrollment procedure in Clinical Trials with Machine Learning Methods Assessing the Overall Burden of Adverse Events in Clinical Trials: Approaches and Challenges Matching-adjusted indirect comparison of endoscopic and craniofacial resection for the treatment of sinonasal cancer invading the skull base Information borrowing in phase II randomized dose-ranging clinical trials in oncology Information borrowing in Bayesian clinical trials: choice of tuning parameters for the robust mixture prior A Bayesian approach to decision making in early development clinical trials : An R solution. Designing Clinical Trials in R with rpact and crmPack Leveraging on historical controls in the design and analysis of phase II clinical trials Design of a research project to evaluate the statistical utility after transformation of a CDISC database into OMOP format Introducing CAMIS: an open-source, community endeavor for Comparing Analysis Method Implementations in Software Assessing covariates influence on cure probability in mixture cure models using martingale difference correlation Aligning Estimators to Treatment Effects in the presence of Intercurrent Events in the Analyses of Safety Outcomes CUtools: an R package for clinical utility analysis of predictive models Impact of Particulate Matter 2.5 Levels on Chronic Obstructive Pulmonary Disease: An Analysis of Nationwide Claims Data in Thailand Changes in health services use of a cohort of COPD patients from a pre-pandemic to a COVID-19 pandemic period The ISARIC Clinical Epidemiology Platform: Standardized Analytical Pipelines for Rapid Outbreak Response Topic modelling and time-series analysis to explore methodological trend evolution Post-stroke facial palsy: prevalence on admission, risk factors, and recovery with hyperacute treatments Evaluating Outlier Detection Methods in Real-World Growth Data: A Sensitivity Analysis of Imperfect Data in a Cluster Randomised Controlled Trial Latent class analysis on intersectional social identities and mental wellbeing among ethnic minority youth in Aotearoa New Zealand Using multiple imputation in real-word data studies to aid in the identification of predictors of response while addressing missing data An imputation method for heterogeneous studies in Network Meta-Analysis: A Fully Conditional Specification approach using distance metrics Impact of lack of measurement invariance on causal inference in randomized controlled-trials including patient-reported outcome measures: a simulation study Evaluation of the Psychometric Qualities of Idiographic Patient Reported Outcome Measures (I-PROMs) for Patients Monitoring: PSYCHLOPS example Bias in the estimation of a psychometric function when using the PSI-method under optimal conditions – a simulation study Psychometric properties confirmation of the Multiple Sclerosis Autonomy Scale (MSAS) questionnaire evaluating patient autonomy in multiple sclerosis (MS) Learning heterogeneous treatment effect from multiple randomized trials to inform healthcare decision-making: implications and estimation methods Multiple imputation of missing viral load measurements in HIV treatment trials: a comparison of strategies A novel approach for assessing inconsistency in network meta-analysis: Application to comparative effectiveness analysis of antihypertensive treatments Investigating (bio)statistical literacy among health researchers in a Belgian university context: A framework and study protocol Balneotherapy for Peripheral Vascular Diseases: A Systematic Review with a Focus on Peripheral Arterial Disease and Chronic Venous Insufficiency Binomial Sum Variance Inequality correction of 95% CIs of percentages in multicentre studies ensures approximately 95% coverage with minimal width Sample size calculation methods for clinical trials using co-primary count endpoints Analysis of Composite Endpoint in Cardiovascular Device Clinical Trials Bayesian predictive monitoring using two-dimensional index for single-arm trial with bivariate binary outcomes Optimising covariate allocation at design stage using Fisher Information Matrix for Non-Linear Mixed Effects Models in pharmacometrics Unbiased Estimation for Hierarchical Models in Clinical Trials Sample size re-estimation for McNemar's test in a prospective randomized clinical trial on childhood glaucoma Bayesian bivariate analysis of phase II basket trials enabling borrowing of information Usefulness of the blinded sample size re-estimation for dose-response trials with MCP-Mod Quantification of allocation bias in clinical trials under a response-adaptive randomization procedure for binary response variables Assessment of Assay Sensitivity in Non-Inferiority Trials Using Aggregate Data from a Historical Trial: A Population Adjustment Approach Exploring methods for borrowing evidence across baskets or subgroups in a clinical trial: a simulation study Comparing The ED50 Between Treatment Groups Using Sequential Allocation Trials. A pre-study look into post-study knowledge: communicating the use(fulness) of pre-posteriors in early development design discussions Estimation and testing methods for delayed-start design as an alternative to single-arm trials in small clinical trials Dealing with missing values in adaptive N-of-1 trials Adaptive clinical trial design with delayed treatment effects using elicited prior distributions |
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| 1:00pm - 2:00pm |
Lunch |
Poster Exhibition: M / Monday posters Location: Poster Location Longitudinal Psychological Status and Risk of Major Cardiovascular Events (MCE) in Individuals with Pre-Existing Myocardial Infarction: A Joint Modeling Approach Cardio-metabolic traits and its socioeconomic differentials among school children including MONW phenotypes in India: A baseline characteristics of LEAP-C cohort External validation of SMART2 model for recurrent cardiovascular risk Multi-disease risk models to target concomitant diseases and their interactions: Insights on cardio-renal-metabolic syndrome in England Machine learning methods for analyzing longitudinal health data streams: A comparative study Evaluating the fairness of a clinical prediction model for outcomes following psychological treatment in the UK’s National Health Service Multiple Imputation vs. Machine Learning for Handling Missing Data in Prediction Modelling: Which Best Balances Stability, Performance, and Computational Efficiency? Estimating rates of dental treatment and unmet dental need in a spatially explicit model in children in England, 2016-2018 Statistical Approach to Assess the Impact of Hospital Settings on Optimal Staffing Levels Real-time predictions of bed occupancy in hospitals. Positive and negative predictive values of diagnostic tests using area under the curve Freely accessible software for recruitment prediction and recruitment monitoring: Is it necessary? On moderation in a Bayesian log-contrast compositional model with a total. Interaction between extreme temperatures and pollutants on mortality Graphical inference in nonparametric hypothesis testing: A two-dimensional grid framework for analysis and visualization On regression analysis of interval-valued data based on order statistics Two-sided Beyesian simultaneous credible bands in linear regression model Cell composition analysis with unmeasured confounding Temporal transcriptomic analysis of microexon alternative splicing in mouse neurodevelopmental genes A Robust Method for Accurate Reconstruction of 3D Genome Conformation from Hi-C Data Balancing Accuracy, Clinical Utility, and Explainability: A Machine Learning Approach to Prostate Cancer Prediction Development of a thyroid cancer recurrence prediction calculator: A regression approach A comparison of methods for modelling multi-state cancer progression using screening data with censoring after intervention ADHD and 10–Year Disease Progression from Initiating Pharmacotherapy for Hypertension to Death: A Multistate Modelling Analysis Understanding PSA Dynamics: Integrating Longitudinal Trajectories, Testing Patterns, and Disease Progression. Joint Modeling for Principal Stratification: Analyzing Stroke Events in CADASIL Patients Across NOTCH3 Variants Challenges in modelling neuropsychiatric symptoms in early Alzheimer's Disease Network models to decipher the Human exposome : application to food exposome patterns in the general population Study brain connectivity changes in Dementia with Lewy Bodies with Functional Conditional Gaussian Graphical Models LongiSurvSHAP: Explaining Survival Models with Longitudinal Features Prognostic Models for Recurrent Event Data Unlocking diagnosis code for longitudinal modeling through representations from large language models Machine Learning Perspectives in Survival Prediction Model Selection: Frequentist vs. Bayesian Approach Non-parametric methods for comparing survival functions with censored data: Exhaustive simulation of all possible beyond-observed censoring scenarios and computational analysis Tree-based methods for length-biased survival data Evaluating different pragmatic approaches for selecting the truncation time of the restricted mean survival time in randomized controlled trials Identifying risk factors for hospital readmission in home-based care: a study from a monographic paediatric cancer centre A web-application for predicting Serious Adverse Event for guiding the enrollment procedure in Clinical Trials with Machine Learning Methods Assessing the Overall Burden of Adverse Events in Clinical Trials: Approaches and Challenges Matching-adjusted indirect comparison of endoscopic and craniofacial resection for the treatment of sinonasal cancer invading the skull base Information borrowing in phase II randomized dose-ranging clinical trials in oncology Information borrowing in Bayesian clinical trials: choice of tuning parameters for the robust mixture prior A Bayesian approach to decision making in early development clinical trials : An R solution. Designing Clinical Trials in R with rpact and crmPack Leveraging on historical controls in the design and analysis of phase II clinical trials Design of a research project to evaluate the statistical utility after transformation of a CDISC database into OMOP format Introducing CAMIS: an open-source, community endeavor for Comparing Analysis Method Implementations in Software Assessing covariates influence on cure probability in mixture cure models using martingale difference correlation Aligning Estimators to Treatment Effects in the presence of Intercurrent Events in the Analyses of Safety Outcomes CUtools: an R package for clinical utility analysis of predictive models Impact of Particulate Matter 2.5 Levels on Chronic Obstructive Pulmonary Disease: An Analysis of Nationwide Claims Data in Thailand Changes in health services use of a cohort of COPD patients from a pre-pandemic to a COVID-19 pandemic period The ISARIC Clinical Epidemiology Platform: Standardized Analytical Pipelines for Rapid Outbreak Response Topic modelling and time-series analysis to explore methodological trend evolution Post-stroke facial palsy: prevalence on admission, risk factors, and recovery with hyperacute treatments Evaluating Outlier Detection Methods in Real-World Growth Data: A Sensitivity Analysis of Imperfect Data in a Cluster Randomised Controlled Trial Latent class analysis on intersectional social identities and mental wellbeing among ethnic minority youth in Aotearoa New Zealand Using multiple imputation in real-word data studies to aid in the identification of predictors of response while addressing missing data An imputation method for heterogeneous studies in Network Meta-Analysis: A Fully Conditional Specification approach using distance metrics Impact of lack of measurement invariance on causal inference in randomized controlled-trials including patient-reported outcome measures: a simulation study Evaluation of the Psychometric Qualities of Idiographic Patient Reported Outcome Measures (I-PROMs) for Patients Monitoring: PSYCHLOPS example Bias in the estimation of a psychometric function when using the PSI-method under optimal conditions – a simulation study Psychometric properties confirmation of the Multiple Sclerosis Autonomy Scale (MSAS) questionnaire evaluating patient autonomy in multiple sclerosis (MS) Learning heterogeneous treatment effect from multiple randomized trials to inform healthcare decision-making: implications and estimation methods Multiple imputation of missing viral load measurements in HIV treatment trials: a comparison of strategies A novel approach for assessing inconsistency in network meta-analysis: Application to comparative effectiveness analysis of antihypertensive treatments Investigating (bio)statistical literacy among health researchers in a Belgian university context: A framework and study protocol Balneotherapy for Peripheral Vascular Diseases: A Systematic Review with a Focus on Peripheral Arterial Disease and Chronic Venous Insufficiency Binomial Sum Variance Inequality correction of 95% CIs of percentages in multicentre studies ensures approximately 95% coverage with minimal width Sample size calculation methods for clinical trials using co-primary count endpoints Analysis of Composite Endpoint in Cardiovascular Device Clinical Trials Bayesian predictive monitoring using two-dimensional index for single-arm trial with bivariate binary outcomes Optimising covariate allocation at design stage using Fisher Information Matrix for Non-Linear Mixed Effects Models in pharmacometrics Unbiased Estimation for Hierarchical Models in Clinical Trials Sample size re-estimation for McNemar's test in a prospective randomized clinical trial on childhood glaucoma Bayesian bivariate analysis of phase II basket trials enabling borrowing of information Usefulness of the blinded sample size re-estimation for dose-response trials with MCP-Mod Quantification of allocation bias in clinical trials under a response-adaptive randomization procedure for binary response variables Assessment of Assay Sensitivity in Non-Inferiority Trials Using Aggregate Data from a Historical Trial: A Population Adjustment Approach Exploring methods for borrowing evidence across baskets or subgroups in a clinical trial: a simulation study Comparing The ED50 Between Treatment Groups Using Sequential Allocation Trials. A pre-study look into post-study knowledge: communicating the use(fulness) of pre-posteriors in early development design discussions Estimation and testing methods for delayed-start design as an alternative to single-arm trials in small clinical trials Dealing with missing values in adaptive N-of-1 trials Adaptive clinical trial design with delayed treatment effects using elicited prior distributions |
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| 2:00pm - 3:30pm |
AI-driven multi-omics data integration Location: Biozentrum U1.111 Generative AI for Unlocking the Complexity of Cells Machine Learning for Multi-Omics Integration: Advancing Rare Disease Diagnostics in Pediatric Acute Care Correspondence problems in multi-omic data |
Defining estimands for clinical trials Location: Biozentrum U1.131 What is the estimand for the proportional odds model? On the use of the net treatment benefit as a treatment-effect measure in randomized clinical trials Challenges and opportunities in defining new estimands for longitudinal outcomes truncated by death What estimands can and should be used when interventions may be given more than once? Current practice around the use of estimands in cluster randomised trials, and the impact of informative cluster size on inferences |
Adaptive and multi-arm multi-stage trials Location: Biozentrum U1.141 Confidence intervals in two-stage adaptive enrichment designs Dynamic Bayesian Sample Size Re-Estimation: Balancing Historical and Real-Time Data in Adaptive Clinical Trials MAMS with patient reported outcomes and treatments with different modalities: how should we handle a differential placebo effect? Multi-arm multi-stage (MAMS) randomised selection designs: With an application to miscarriage and surgical platform trials A test for treatment differences using allocation probabilities in response-adaptive clinical trials |
Causal inference: target trial emulation Location: Biozentrum U1.101 Inference on sustained treatment strategies, with a case study on young women with breast cancer An overlooked bias in target trial emulations and how to fix it Model-free estimands for target trial analysis Target trial emulation: optimising methods for estimating treatment effects using data from the UK Cystic Fibrosis Registry Target Trials and Structural Nested Models: Emulating RCTs using Observational Longitudinal Data |
| Meta-analysis 1 Location: ETH E27 Precision Of Treatment Hierarchy: A Metric for Quantifying Certainty in Treatment Hierarchies from Network Meta-Analysis Extending P-Scores for Ranking Diagnostic Tests in Network Meta-Analysis Resolving conflicting treatment hierarchies across multiple outcomes in multivariate network meta-analysis A novel approach for modelling components of complex interventions in network meta-analysis The impact of using different random effects models in meta-analysis |
Prediction / prognostic modelling 2 Location: ETH E23 Assessing time-dependent discrimination of prognostic model with intercurrent treatment: use of multi-state modelling for inverse probability censoring weighting Evaluating the discrimination of prediction models for recurrent medical events A Novel Dynamic Prediction Model Based on Interpretable Deep Learning Using Restricted Mean Survival Time Correcting for differential diagnosis bias across protected attributes in clinical prediction models using cancer stage information and causal inference |
Joint / longitudinal modelling Location: ETH E21 Assessing surrogacy from joint modelling and mediation analysis when surrogates are either censored event times or longitudinal biomarker: cancer application Joint Modelling Using Semiparametric Accelerated Failure Time Approaches: Application to Health-Related Quality of Life Analysis Using Joint Models to Assess Delayed Initiation of Salvage Therapy following Biochemical Recurrence for Prostate Cancer. Faster Estimation of Quasi-Monte Carlo Methods for Joint Models of Multivariate Longitudinal Data and Penalized Cox Regression Regularization and Flexible Methods to Improve Complete Cancer Prevalence Predictions in the Prevalence Incidence Analysis Model |
Poster Exhibition: M / Monday posters Location: Poster Location Longitudinal Psychological Status and Risk of Major Cardiovascular Events (MCE) in Individuals with Pre-Existing Myocardial Infarction: A Joint Modeling Approach Cardio-metabolic traits and its socioeconomic differentials among school children including MONW phenotypes in India: A baseline characteristics of LEAP-C cohort External validation of SMART2 model for recurrent cardiovascular risk Multi-disease risk models to target concomitant diseases and their interactions: Insights on cardio-renal-metabolic syndrome in England Machine learning methods for analyzing longitudinal health data streams: A comparative study Evaluating the fairness of a clinical prediction model for outcomes following psychological treatment in the UK’s National Health Service Multiple Imputation vs. Machine Learning for Handling Missing Data in Prediction Modelling: Which Best Balances Stability, Performance, and Computational Efficiency? Estimating rates of dental treatment and unmet dental need in a spatially explicit model in children in England, 2016-2018 Statistical Approach to Assess the Impact of Hospital Settings on Optimal Staffing Levels Real-time predictions of bed occupancy in hospitals. Positive and negative predictive values of diagnostic tests using area under the curve Freely accessible software for recruitment prediction and recruitment monitoring: Is it necessary? On moderation in a Bayesian log-contrast compositional model with a total. Interaction between extreme temperatures and pollutants on mortality Graphical inference in nonparametric hypothesis testing: A two-dimensional grid framework for analysis and visualization On regression analysis of interval-valued data based on order statistics Two-sided Beyesian simultaneous credible bands in linear regression model Cell composition analysis with unmeasured confounding Temporal transcriptomic analysis of microexon alternative splicing in mouse neurodevelopmental genes A Robust Method for Accurate Reconstruction of 3D Genome Conformation from Hi-C Data Balancing Accuracy, Clinical Utility, and Explainability: A Machine Learning Approach to Prostate Cancer Prediction Development of a thyroid cancer recurrence prediction calculator: A regression approach A comparison of methods for modelling multi-state cancer progression using screening data with censoring after intervention ADHD and 10–Year Disease Progression from Initiating Pharmacotherapy for Hypertension to Death: A Multistate Modelling Analysis Understanding PSA Dynamics: Integrating Longitudinal Trajectories, Testing Patterns, and Disease Progression. Joint Modeling for Principal Stratification: Analyzing Stroke Events in CADASIL Patients Across NOTCH3 Variants Challenges in modelling neuropsychiatric symptoms in early Alzheimer's Disease Network models to decipher the Human exposome : application to food exposome patterns in the general population Study brain connectivity changes in Dementia with Lewy Bodies with Functional Conditional Gaussian Graphical Models LongiSurvSHAP: Explaining Survival Models with Longitudinal Features Prognostic Models for Recurrent Event Data Unlocking diagnosis code for longitudinal modeling through representations from large language models Machine Learning Perspectives in Survival Prediction Model Selection: Frequentist vs. Bayesian Approach Non-parametric methods for comparing survival functions with censored data: Exhaustive simulation of all possible beyond-observed censoring scenarios and computational analysis Tree-based methods for length-biased survival data Evaluating different pragmatic approaches for selecting the truncation time of the restricted mean survival time in randomized controlled trials Identifying risk factors for hospital readmission in home-based care: a study from a monographic paediatric cancer centre A web-application for predicting Serious Adverse Event for guiding the enrollment procedure in Clinical Trials with Machine Learning Methods Assessing the Overall Burden of Adverse Events in Clinical Trials: Approaches and Challenges Matching-adjusted indirect comparison of endoscopic and craniofacial resection for the treatment of sinonasal cancer invading the skull base Information borrowing in phase II randomized dose-ranging clinical trials in oncology Information borrowing in Bayesian clinical trials: choice of tuning parameters for the robust mixture prior A Bayesian approach to decision making in early development clinical trials : An R solution. Designing Clinical Trials in R with rpact and crmPack Leveraging on historical controls in the design and analysis of phase II clinical trials Design of a research project to evaluate the statistical utility after transformation of a CDISC database into OMOP format Introducing CAMIS: an open-source, community endeavor for Comparing Analysis Method Implementations in Software Assessing covariates influence on cure probability in mixture cure models using martingale difference correlation Aligning Estimators to Treatment Effects in the presence of Intercurrent Events in the Analyses of Safety Outcomes CUtools: an R package for clinical utility analysis of predictive models Impact of Particulate Matter 2.5 Levels on Chronic Obstructive Pulmonary Disease: An Analysis of Nationwide Claims Data in Thailand Changes in health services use of a cohort of COPD patients from a pre-pandemic to a COVID-19 pandemic period The ISARIC Clinical Epidemiology Platform: Standardized Analytical Pipelines for Rapid Outbreak Response Topic modelling and time-series analysis to explore methodological trend evolution Post-stroke facial palsy: prevalence on admission, risk factors, and recovery with hyperacute treatments Evaluating Outlier Detection Methods in Real-World Growth Data: A Sensitivity Analysis of Imperfect Data in a Cluster Randomised Controlled Trial Latent class analysis on intersectional social identities and mental wellbeing among ethnic minority youth in Aotearoa New Zealand Using multiple imputation in real-word data studies to aid in the identification of predictors of response while addressing missing data An imputation method for heterogeneous studies in Network Meta-Analysis: A Fully Conditional Specification approach using distance metrics Impact of lack of measurement invariance on causal inference in randomized controlled-trials including patient-reported outcome measures: a simulation study Evaluation of the Psychometric Qualities of Idiographic Patient Reported Outcome Measures (I-PROMs) for Patients Monitoring: PSYCHLOPS example Bias in the estimation of a psychometric function when using the PSI-method under optimal conditions – a simulation study Psychometric properties confirmation of the Multiple Sclerosis Autonomy Scale (MSAS) questionnaire evaluating patient autonomy in multiple sclerosis (MS) Learning heterogeneous treatment effect from multiple randomized trials to inform healthcare decision-making: implications and estimation methods Multiple imputation of missing viral load measurements in HIV treatment trials: a comparison of strategies A novel approach for assessing inconsistency in network meta-analysis: Application to comparative effectiveness analysis of antihypertensive treatments Investigating (bio)statistical literacy among health researchers in a Belgian university context: A framework and study protocol Balneotherapy for Peripheral Vascular Diseases: A Systematic Review with a Focus on Peripheral Arterial Disease and Chronic Venous Insufficiency Binomial Sum Variance Inequality correction of 95% CIs of percentages in multicentre studies ensures approximately 95% coverage with minimal width Sample size calculation methods for clinical trials using co-primary count endpoints Analysis of Composite Endpoint in Cardiovascular Device Clinical Trials Bayesian predictive monitoring using two-dimensional index for single-arm trial with bivariate binary outcomes Optimising covariate allocation at design stage using Fisher Information Matrix for Non-Linear Mixed Effects Models in pharmacometrics Unbiased Estimation for Hierarchical Models in Clinical Trials Sample size re-estimation for McNemar's test in a prospective randomized clinical trial on childhood glaucoma Bayesian bivariate analysis of phase II basket trials enabling borrowing of information Usefulness of the blinded sample size re-estimation for dose-response trials with MCP-Mod Quantification of allocation bias in clinical trials under a response-adaptive randomization procedure for binary response variables Assessment of Assay Sensitivity in Non-Inferiority Trials Using Aggregate Data from a Historical Trial: A Population Adjustment Approach Exploring methods for borrowing evidence across baskets or subgroups in a clinical trial: a simulation study Comparing The ED50 Between Treatment Groups Using Sequential Allocation Trials. A pre-study look into post-study knowledge: communicating the use(fulness) of pre-posteriors in early development design discussions Estimation and testing methods for delayed-start design as an alternative to single-arm trials in small clinical trials Dealing with missing values in adaptive N-of-1 trials Adaptive clinical trial design with delayed treatment effects using elicited prior distributions |
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| 3:30pm - 4:00pm |
Coffee Break |
Poster Exhibition: M / Monday posters Location: Poster Location Longitudinal Psychological Status and Risk of Major Cardiovascular Events (MCE) in Individuals with Pre-Existing Myocardial Infarction: A Joint Modeling Approach Cardio-metabolic traits and its socioeconomic differentials among school children including MONW phenotypes in India: A baseline characteristics of LEAP-C cohort External validation of SMART2 model for recurrent cardiovascular risk Multi-disease risk models to target concomitant diseases and their interactions: Insights on cardio-renal-metabolic syndrome in England Machine learning methods for analyzing longitudinal health data streams: A comparative study Evaluating the fairness of a clinical prediction model for outcomes following psychological treatment in the UK’s National Health Service Multiple Imputation vs. Machine Learning for Handling Missing Data in Prediction Modelling: Which Best Balances Stability, Performance, and Computational Efficiency? Estimating rates of dental treatment and unmet dental need in a spatially explicit model in children in England, 2016-2018 Statistical Approach to Assess the Impact of Hospital Settings on Optimal Staffing Levels Real-time predictions of bed occupancy in hospitals. Positive and negative predictive values of diagnostic tests using area under the curve Freely accessible software for recruitment prediction and recruitment monitoring: Is it necessary? On moderation in a Bayesian log-contrast compositional model with a total. Interaction between extreme temperatures and pollutants on mortality Graphical inference in nonparametric hypothesis testing: A two-dimensional grid framework for analysis and visualization On regression analysis of interval-valued data based on order statistics Two-sided Beyesian simultaneous credible bands in linear regression model Cell composition analysis with unmeasured confounding Temporal transcriptomic analysis of microexon alternative splicing in mouse neurodevelopmental genes A Robust Method for Accurate Reconstruction of 3D Genome Conformation from Hi-C Data Balancing Accuracy, Clinical Utility, and Explainability: A Machine Learning Approach to Prostate Cancer Prediction Development of a thyroid cancer recurrence prediction calculator: A regression approach A comparison of methods for modelling multi-state cancer progression using screening data with censoring after intervention ADHD and 10–Year Disease Progression from Initiating Pharmacotherapy for Hypertension to Death: A Multistate Modelling Analysis Understanding PSA Dynamics: Integrating Longitudinal Trajectories, Testing Patterns, and Disease Progression. Joint Modeling for Principal Stratification: Analyzing Stroke Events in CADASIL Patients Across NOTCH3 Variants Challenges in modelling neuropsychiatric symptoms in early Alzheimer's Disease Network models to decipher the Human exposome : application to food exposome patterns in the general population Study brain connectivity changes in Dementia with Lewy Bodies with Functional Conditional Gaussian Graphical Models LongiSurvSHAP: Explaining Survival Models with Longitudinal Features Prognostic Models for Recurrent Event Data Unlocking diagnosis code for longitudinal modeling through representations from large language models Machine Learning Perspectives in Survival Prediction Model Selection: Frequentist vs. Bayesian Approach Non-parametric methods for comparing survival functions with censored data: Exhaustive simulation of all possible beyond-observed censoring scenarios and computational analysis Tree-based methods for length-biased survival data Evaluating different pragmatic approaches for selecting the truncation time of the restricted mean survival time in randomized controlled trials Identifying risk factors for hospital readmission in home-based care: a study from a monographic paediatric cancer centre A web-application for predicting Serious Adverse Event for guiding the enrollment procedure in Clinical Trials with Machine Learning Methods Assessing the Overall Burden of Adverse Events in Clinical Trials: Approaches and Challenges Matching-adjusted indirect comparison of endoscopic and craniofacial resection for the treatment of sinonasal cancer invading the skull base Information borrowing in phase II randomized dose-ranging clinical trials in oncology Information borrowing in Bayesian clinical trials: choice of tuning parameters for the robust mixture prior A Bayesian approach to decision making in early development clinical trials : An R solution. Designing Clinical Trials in R with rpact and crmPack Leveraging on historical controls in the design and analysis of phase II clinical trials Design of a research project to evaluate the statistical utility after transformation of a CDISC database into OMOP format Introducing CAMIS: an open-source, community endeavor for Comparing Analysis Method Implementations in Software Assessing covariates influence on cure probability in mixture cure models using martingale difference correlation Aligning Estimators to Treatment Effects in the presence of Intercurrent Events in the Analyses of Safety Outcomes CUtools: an R package for clinical utility analysis of predictive models Impact of Particulate Matter 2.5 Levels on Chronic Obstructive Pulmonary Disease: An Analysis of Nationwide Claims Data in Thailand Changes in health services use of a cohort of COPD patients from a pre-pandemic to a COVID-19 pandemic period The ISARIC Clinical Epidemiology Platform: Standardized Analytical Pipelines for Rapid Outbreak Response Topic modelling and time-series analysis to explore methodological trend evolution Post-stroke facial palsy: prevalence on admission, risk factors, and recovery with hyperacute treatments Evaluating Outlier Detection Methods in Real-World Growth Data: A Sensitivity Analysis of Imperfect Data in a Cluster Randomised Controlled Trial Latent class analysis on intersectional social identities and mental wellbeing among ethnic minority youth in Aotearoa New Zealand Using multiple imputation in real-word data studies to aid in the identification of predictors of response while addressing missing data An imputation method for heterogeneous studies in Network Meta-Analysis: A Fully Conditional Specification approach using distance metrics Impact of lack of measurement invariance on causal inference in randomized controlled-trials including patient-reported outcome measures: a simulation study Evaluation of the Psychometric Qualities of Idiographic Patient Reported Outcome Measures (I-PROMs) for Patients Monitoring: PSYCHLOPS example Bias in the estimation of a psychometric function when using the PSI-method under optimal conditions – a simulation study Psychometric properties confirmation of the Multiple Sclerosis Autonomy Scale (MSAS) questionnaire evaluating patient autonomy in multiple sclerosis (MS) Learning heterogeneous treatment effect from multiple randomized trials to inform healthcare decision-making: implications and estimation methods Multiple imputation of missing viral load measurements in HIV treatment trials: a comparison of strategies A novel approach for assessing inconsistency in network meta-analysis: Application to comparative effectiveness analysis of antihypertensive treatments Investigating (bio)statistical literacy among health researchers in a Belgian university context: A framework and study protocol Balneotherapy for Peripheral Vascular Diseases: A Systematic Review with a Focus on Peripheral Arterial Disease and Chronic Venous Insufficiency Binomial Sum Variance Inequality correction of 95% CIs of percentages in multicentre studies ensures approximately 95% coverage with minimal width Sample size calculation methods for clinical trials using co-primary count endpoints Analysis of Composite Endpoint in Cardiovascular Device Clinical Trials Bayesian predictive monitoring using two-dimensional index for single-arm trial with bivariate binary outcomes Optimising covariate allocation at design stage using Fisher Information Matrix for Non-Linear Mixed Effects Models in pharmacometrics Unbiased Estimation for Hierarchical Models in Clinical Trials Sample size re-estimation for McNemar's test in a prospective randomized clinical trial on childhood glaucoma Bayesian bivariate analysis of phase II basket trials enabling borrowing of information Usefulness of the blinded sample size re-estimation for dose-response trials with MCP-Mod Quantification of allocation bias in clinical trials under a response-adaptive randomization procedure for binary response variables Assessment of Assay Sensitivity in Non-Inferiority Trials Using Aggregate Data from a Historical Trial: A Population Adjustment Approach Exploring methods for borrowing evidence across baskets or subgroups in a clinical trial: a simulation study Comparing The ED50 Between Treatment Groups Using Sequential Allocation Trials. A pre-study look into post-study knowledge: communicating the use(fulness) of pre-posteriors in early development design discussions Estimation and testing methods for delayed-start design as an alternative to single-arm trials in small clinical trials Dealing with missing values in adaptive N-of-1 trials Adaptive clinical trial design with delayed treatment effects using elicited prior distributions |
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| 4:00pm - 5:30pm |
Prediction modelling meets causal inference for clinical decision making Location: Biozentrum U1.111 Clinical applications of predictions under interventions Dynamic Prediction of Survival Benefit to Inform Liver Transplant Decisions in Hepatocellular Carcinoma Patients From prediction to treatment decision: aligning development, evaluation and monitoring |
Estimands: causal and multiple imputation approaches Location: Biozentrum U1.131 The role of post intercurrent event data in the estimation of hypothetical estimands in clinical trials Bringing together estimands, causal inference and pharmacometric modeling and simulation Nonparanormal Adjusted Marginal Inference Estimation of effects with treatment policy handling for binary outcomes using multiple imputation Can Treatment Effect Testing in Trials with Intercurrent Events Be Nearly Assumption-Free? |
Clinical trials and regulatory issues Location: Biozentrum U1.141 Compatible Effect Estimation and Hypothesis Testing in Drug Regulation Opportunities to speed up IVD adoption and patient access in the UK: the pre-eclampsia testing timeline Statistical review of regulatory requirements for AI diagnosis Validating Physiologically-based Pharmacokinetic Models using the Continuous Ranked Probability Score: Beyond Being Correct on Average Conditional Marketing Authorisation based on the Intermediate Endpoint of a Randomised Clinical Trial: Dual or Co-Primary Endpoints? |
Model selection and simulations Location: Biozentrum U1.101 A systematic review of variable and functional form selection methods used in Covid-19 prognostic models Robust and Flexible Extension of M-quantile Regression with Adaptive Class of Regularization Robust standard errors for coefficients of selected and unselected predictors after variable selection for binary outcomes The “multi-performance plot” in simulation studies: a compact visualisation of up to seven performance measures comparing multiple statistical methods What is the impact of increasing numbers of auxiliary variables for an explanatory variable in imputation models? |
| Bayesian methods 1 Location: ETH E27 A Bayesian model for surrogate endpoint evaluation in mixed biomarker patient populations Extending Bayesian Causal Forests for Longitudinal Data Analysis: A Case Study in Multiple Sclerosis A Bayesian framework for measuring the information cost of interim decisions in group sequential trials Bayesian semiparametric modelling of biomarker variability in joint models for longitudinal and survival data Bayesian analysis of the causal reference-based model for missing data in clinical trials |
Multi-omics data integration Location: ETH E23 Unsupervised Factor-Based Methods for Multi-Omics Data Integration Multi-modal integration reveals the joint role of electrocardiogram, imaging and genetics in cardiovascular risk Analyzing Protein Folding Dynamics Using Multi-Dimensional Varying Coefficient Models X-Med: Cross-modal integration for sequential intelligence in aftercare of kidney transplant recipients Modeling Interdependencies in Multiomic Spatial Analysis |
Biomarker studies & diagnostic tests Location: ETH E21 Assessing diagnostic accuracy for three-class classification problems Biological Age Estimation in the Estonian Biobank Based on NMR Metabolomics Data and Phenotype Bézier curve parametric method for approximating ROC curves in the context of multiple clinical decision thresholds Deriving Cost-effective Neyman-Pearson Classifier with Multiple-Modality Detection Tools Improving Biomarker Diagnostic Accuracy with the Likelihood Ratio Transformation |
Poster Exhibition: M / Monday posters Location: Poster Location Longitudinal Psychological Status and Risk of Major Cardiovascular Events (MCE) in Individuals with Pre-Existing Myocardial Infarction: A Joint Modeling Approach Cardio-metabolic traits and its socioeconomic differentials among school children including MONW phenotypes in India: A baseline characteristics of LEAP-C cohort External validation of SMART2 model for recurrent cardiovascular risk Multi-disease risk models to target concomitant diseases and their interactions: Insights on cardio-renal-metabolic syndrome in England Machine learning methods for analyzing longitudinal health data streams: A comparative study Evaluating the fairness of a clinical prediction model for outcomes following psychological treatment in the UK’s National Health Service Multiple Imputation vs. Machine Learning for Handling Missing Data in Prediction Modelling: Which Best Balances Stability, Performance, and Computational Efficiency? Estimating rates of dental treatment and unmet dental need in a spatially explicit model in children in England, 2016-2018 Statistical Approach to Assess the Impact of Hospital Settings on Optimal Staffing Levels Real-time predictions of bed occupancy in hospitals. Positive and negative predictive values of diagnostic tests using area under the curve Freely accessible software for recruitment prediction and recruitment monitoring: Is it necessary? On moderation in a Bayesian log-contrast compositional model with a total. Interaction between extreme temperatures and pollutants on mortality Graphical inference in nonparametric hypothesis testing: A two-dimensional grid framework for analysis and visualization On regression analysis of interval-valued data based on order statistics Two-sided Beyesian simultaneous credible bands in linear regression model Cell composition analysis with unmeasured confounding Temporal transcriptomic analysis of microexon alternative splicing in mouse neurodevelopmental genes A Robust Method for Accurate Reconstruction of 3D Genome Conformation from Hi-C Data Balancing Accuracy, Clinical Utility, and Explainability: A Machine Learning Approach to Prostate Cancer Prediction Development of a thyroid cancer recurrence prediction calculator: A regression approach A comparison of methods for modelling multi-state cancer progression using screening data with censoring after intervention ADHD and 10–Year Disease Progression from Initiating Pharmacotherapy for Hypertension to Death: A Multistate Modelling Analysis Understanding PSA Dynamics: Integrating Longitudinal Trajectories, Testing Patterns, and Disease Progression. Joint Modeling for Principal Stratification: Analyzing Stroke Events in CADASIL Patients Across NOTCH3 Variants Challenges in modelling neuropsychiatric symptoms in early Alzheimer's Disease Network models to decipher the Human exposome : application to food exposome patterns in the general population Study brain connectivity changes in Dementia with Lewy Bodies with Functional Conditional Gaussian Graphical Models LongiSurvSHAP: Explaining Survival Models with Longitudinal Features Prognostic Models for Recurrent Event Data Unlocking diagnosis code for longitudinal modeling through representations from large language models Machine Learning Perspectives in Survival Prediction Model Selection: Frequentist vs. Bayesian Approach Non-parametric methods for comparing survival functions with censored data: Exhaustive simulation of all possible beyond-observed censoring scenarios and computational analysis Tree-based methods for length-biased survival data Evaluating different pragmatic approaches for selecting the truncation time of the restricted mean survival time in randomized controlled trials Identifying risk factors for hospital readmission in home-based care: a study from a monographic paediatric cancer centre A web-application for predicting Serious Adverse Event for guiding the enrollment procedure in Clinical Trials with Machine Learning Methods Assessing the Overall Burden of Adverse Events in Clinical Trials: Approaches and Challenges Matching-adjusted indirect comparison of endoscopic and craniofacial resection for the treatment of sinonasal cancer invading the skull base Information borrowing in phase II randomized dose-ranging clinical trials in oncology Information borrowing in Bayesian clinical trials: choice of tuning parameters for the robust mixture prior A Bayesian approach to decision making in early development clinical trials : An R solution. Designing Clinical Trials in R with rpact and crmPack Leveraging on historical controls in the design and analysis of phase II clinical trials Design of a research project to evaluate the statistical utility after transformation of a CDISC database into OMOP format Introducing CAMIS: an open-source, community endeavor for Comparing Analysis Method Implementations in Software Assessing covariates influence on cure probability in mixture cure models using martingale difference correlation Aligning Estimators to Treatment Effects in the presence of Intercurrent Events in the Analyses of Safety Outcomes CUtools: an R package for clinical utility analysis of predictive models Impact of Particulate Matter 2.5 Levels on Chronic Obstructive Pulmonary Disease: An Analysis of Nationwide Claims Data in Thailand Changes in health services use of a cohort of COPD patients from a pre-pandemic to a COVID-19 pandemic period The ISARIC Clinical Epidemiology Platform: Standardized Analytical Pipelines for Rapid Outbreak Response Topic modelling and time-series analysis to explore methodological trend evolution Post-stroke facial palsy: prevalence on admission, risk factors, and recovery with hyperacute treatments Evaluating Outlier Detection Methods in Real-World Growth Data: A Sensitivity Analysis of Imperfect Data in a Cluster Randomised Controlled Trial Latent class analysis on intersectional social identities and mental wellbeing among ethnic minority youth in Aotearoa New Zealand Using multiple imputation in real-word data studies to aid in the identification of predictors of response while addressing missing data An imputation method for heterogeneous studies in Network Meta-Analysis: A Fully Conditional Specification approach using distance metrics Impact of lack of measurement invariance on causal inference in randomized controlled-trials including patient-reported outcome measures: a simulation study Evaluation of the Psychometric Qualities of Idiographic Patient Reported Outcome Measures (I-PROMs) for Patients Monitoring: PSYCHLOPS example Bias in the estimation of a psychometric function when using the PSI-method under optimal conditions – a simulation study Psychometric properties confirmation of the Multiple Sclerosis Autonomy Scale (MSAS) questionnaire evaluating patient autonomy in multiple sclerosis (MS) Learning heterogeneous treatment effect from multiple randomized trials to inform healthcare decision-making: implications and estimation methods Multiple imputation of missing viral load measurements in HIV treatment trials: a comparison of strategies A novel approach for assessing inconsistency in network meta-analysis: Application to comparative effectiveness analysis of antihypertensive treatments Investigating (bio)statistical literacy among health researchers in a Belgian university context: A framework and study protocol Balneotherapy for Peripheral Vascular Diseases: A Systematic Review with a Focus on Peripheral Arterial Disease and Chronic Venous Insufficiency Binomial Sum Variance Inequality correction of 95% CIs of percentages in multicentre studies ensures approximately 95% coverage with minimal width Sample size calculation methods for clinical trials using co-primary count endpoints Analysis of Composite Endpoint in Cardiovascular Device Clinical Trials Bayesian predictive monitoring using two-dimensional index for single-arm trial with bivariate binary outcomes Optimising covariate allocation at design stage using Fisher Information Matrix for Non-Linear Mixed Effects Models in pharmacometrics Unbiased Estimation for Hierarchical Models in Clinical Trials Sample size re-estimation for McNemar's test in a prospective randomized clinical trial on childhood glaucoma Bayesian bivariate analysis of phase II basket trials enabling borrowing of information Usefulness of the blinded sample size re-estimation for dose-response trials with MCP-Mod Quantification of allocation bias in clinical trials under a response-adaptive randomization procedure for binary response variables Assessment of Assay Sensitivity in Non-Inferiority Trials Using Aggregate Data from a Historical Trial: A Population Adjustment Approach Exploring methods for borrowing evidence across baskets or subgroups in a clinical trial: a simulation study Comparing The ED50 Between Treatment Groups Using Sequential Allocation Trials. A pre-study look into post-study knowledge: communicating the use(fulness) of pre-posteriors in early development design discussions Estimation and testing methods for delayed-start design as an alternative to single-arm trials in small clinical trials Dealing with missing values in adaptive N-of-1 trials Adaptive clinical trial design with delayed treatment effects using elicited prior distributions |
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| 6:00pm - 8:30pm |
Welcome reception |
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