Human Biology research has been ongoing for perhaps100 years in one form or another. It has changed and it always will as new questions, theories, methods and collaborations develop. Research in the journal "Human Biology" the predecessor of the AJHB, 50 years ago might look strange to the newer association members in terms of questions addressed and methods used. Yet these rickety roads of the past have led to the slick contemporary research our association's members are conducting now. What makes it slick? Our research today is what it is through both intrinsic development and by borrowings from other disciplines. Research projects my team has conducted illustrate some of this development with their exciting marks of success and painful warts of failure as do other projects by other teams. Each project has a unique developmental history but some tendencies are discernable. Human biologists frequently use a wholistic perspective often in the form of a biocultural approach which is effective, relatively unique in science and highly rewarding. Accepting methodologies from other disciplines has always served well when executed with expertise. Though diverse, we are kept together by our main, integrative questions, those about evolution and phenotypic modification. The new partnership research approach, research conducted in partnership with the people studied, has increased in popularity and application by many. Finally, the creation of teams of specialists brought together by the human biologist, not a jack of all trades and a master of none, but a synthesizer, has made for superhighway research.